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An activator of the HIF signaling pathway, as demonstrated by HRE reporter assay (EC50 = 1.2 µM), HIF-1α nuclear translocation assay (EC50 = 1.3 µM), and increased VEGF expression (EC50 = 1.6 µM); activity is blocked by excess iron, suggesting that ML-228 can chelate iron.

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Product Detail
Thomas No.
C823N16
Mfr. No.
14568-1
Description
ML-228-1 mg
CAS Number
1357171-62-0
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C823N17
Mfr. No.
14568-5
Description
ML-228-5 mg
CAS Number
1357171-62-0
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C823N18
Mfr. No.
14568-10
Description
ML-228-10 mg
CAS Number
1357171-62-0
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C823N19
Mfr. No.
14568-50
Description
ML-228-50 mg
CAS Number
1357171-62-0
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
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