Synonym: (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl)triphenylphosphonium chloride, Mito-TEMPO
CAS Number: 1334850-99-5
Empirical Formula (Hill Notation): C29H35N2O2P · Cl
Molecular Weight: 510.03
Biochem/physiol Actions
MitoTEMPO is a mitochondrially targeted antioxidant, a specific scavenger of mitochondrial superoxide. MitoTEMPO is a combination of the antioxidant piperidine nitroxide TEMPO with the lipophilic cation triphenylphosphonium, giving MitoTEMPO the ability to pass through lipid bilayers with ease and accumulate several hundred-fold in mitochondria. Mitochondrial dysfunction and oxidative stress contribute to a variety of disorders involving cardiovascular, kidney, liver disorders, Parkinson′s and Alzheimer′s disease.
Assay: ≥98% (HPLC)
Form: powder
Storage Condition: desiccated, protect from light
Color: white to light brown
Solubility: H2O: soluble10 mg/mL, clear
Storage Temp.: −20°C