The immune system is an organized complex network of biological structures and processes that protect against disease. For example, cytokine and chemokines mediate interactions between cells directly, regulating target immune cell responses. These responses result in inflammation where the immune system attempts to eradicate foreign antigens and begin the healing process. Consequently, the inflammatory process plays a key protective role in immunity. In addition, cytokine and chemokine research is essential in understanding the immune system and its multi-faceted response to most antigens, as well as disease states such as autoimmune disease, allergic reactions, sepsis, and cancer. The MILLIPLEX® Non-Human Primate Cytokine panel is to be used for the simultaneous quantification of any or all of the following in tissue/cell lysate and culture supernatant samples and serum or plasma samples: G-CSF, GM-CSF, IFNgamma, IL-1beta, IL-1ra, IL-2, IL-4, IL-5, IL-6, IL8, IL-10, IL-12/23(p40), IL-13, IL-15, IL-17A, MCP-1, MIP-1beta, MIP-1alpha, sD40L, TGF-alpha, TNF-alpha, VEGF, and IL-18. The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume. Panel Type: Cytokines/Chemokines
Application:
•Analytes: G-CSF, GM-CSF, IFN-gamma, IL-1RA, IL-1beta, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12/23 (p40), IL-13, IL-15, IL-17, IL-18, MCP-1, MIP-1alpha, MIP-1beta, sCD40L, TGF-alpha, TNF-alpha, VEGF
•Recommended Sample type: Serum, plasma, and cell culture
•Recommended Sample dilution: Neat
•Assay Run Time: Overnight or one day. For best results, an overnight incubation is recommended
•Research Category: Inflammation & Immunology
Legal Information: xMAP is a registered trademark of Luminex Corp
Other Notes: Sensitivity: Refer to kit protocol for sensitivities for individual cytokines/chemokines