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Binds MDM2 (Ki = 0.88 nM), blocking MDM2-p53 protein-protein interaction, leading to p53-dependent cell cycle arrest and/or apoptosis; induces tumor regression in a SJSA-1 xenograft model of osteosarcoma by upregulating the pro-apoptotic protein PUMA.

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Product Detail
Thomas No.
C816R86
Mfr. No.
17473-500
Description
MI-77301-500 µg
Packaging Size
500 µg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C816R87
Mfr. No.
17473-1
Description
MI-77301-1 mg
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C816R88
Mfr. No.
17473-5
Description
MI-77301-5 mg
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C816R89
Mfr. No.
17473-10
Description
MI-77301-10 mg
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
$0.00 (0 Items)
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