Methoxyamine hydrochloride is a commonly used reagent for the generation of oxime derivatives of aldehyde- or ketone-group containing compounds. It is typically employed as an oximation reagent prior to silylation derivatizations.
Synonyms: O-Methylhydroxylamine hydrochloride; Methoxylamine hydrochloride
Molecular Formula: CH5NO · HCl
Molecular Weight: 83.52
Linear Structural Formula: CH3ONH2 · HCl
MDL Number: MFCD00012951
Purity: 97.5-102.5% (AT)
Melting Point: 151-154 C (lit.)
Application: Methoxyamine hydrochloride can be used as:
•A reagent for the preparation of O-methyl oximes.
•A reagent used to make O-methyl oximes from aldehydes or ketones.
•An alkylation reagent.
•It may be used as a derivatization agent to improve the sensitivity of opioids, steroids and ionic metabolites in biological samples and non-volatile flavor compounds in "Angeleno" plum fruit prior to the determination of analytes using gas chromatography-mass spectrometry (GC-MS) technique.
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