Methacholine chloride is a cholinergic agonist and parasympathomimetic bronchoconstrictor. A metabolically stable analog of acetylcholine. Its ability to constrict airway smooth muscle is used to assess bronchial reactivity in the laboratory and clinically.
CAS Number: 62-5-1
Molecular Formula: C8H18ClNO2
Molecular Weight: 195.7
Beilstein Registry Number: 4162373
EC Number: 200-537-2
MDL Number: MFCD00011817
Applications
Methacholine is primarily used to diagnose bronchial hyperreactivity,which is the hallmark of asthma and also occurs in chronic obstructive pulmonary disease.
Biochem/physiol Actions
Metabolically stable analog of acetylcholine; muscarinic agonist. Its ability to constrict airway smooth muscle is used to assess bronchial reactivity in the laboratory and clinically.