This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Synonyms: 1,1-Dimethylbiguanide hydrochloride; Metformin
Molecular Formula: C4H11N5 · HCl
Molecular Weight: 165.62
Linear Structural Formula: NH2C(=NH)NHC(=NH)N(CH3)2 · HCl
MDL Number: MFCD00012582
Melting Point: 223-226 C (lit.)
Storage: 2-8C
Biochem Physiol Actions: Metformin is an antidiabetic agent that reduces blood glucose levels and improves insulin sensitivity. Its metabolic effects, including the inhibition of hepatic gluconeogenesis, are mediated at least in part by activation of the LKB1-AMPK (AMP-activated protein kinase) pathway. Activation of this pathway also appears to be involved in the antiproliferative and proapoptotic actions of metformin in cancer cell lines.
Other Notes: Sales restrictions may apply.