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A non-peptide inhibitor of BACE1 (IC50 = 239 nM) that demonstrates ~10-fold selectivity over BACE2 and >50-fold selectivity over other aspartyl proteases; decreases Aβ in APP-overexpressing cells and transgenic animal models and reduces C99 and sAPPβ, the two primary APP cleavage products generated by BACE1.

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Product Detail
Thomas No.
C817X56
Mfr. No.
16712-1
Description
LY2811376-1 mg
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X57
Mfr. No.
16712-5
Description
LY2811376-5 mg
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X58
Mfr. No.
16712-10
Description
LY2811376-10 mg
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C817X59
Mfr. No.
16712-50
Description
LY2811376-50 mg
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
$0.00 (0 Items)
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