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MilliporeSigma

LY2584702 tosylate >=98% (HPLC)

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Synonyms: 4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine, 4-methylbenzenesulfonate (1:1); LY 2584702 tosylate; LY 2779964; LY-2584702 tosylate; LY-2779964; LY2779964; LYS6K2 tosylate

Molecular Formula: C21H19F4N7 · C7H8O3S

Molecular Weight: 617.62

Linear Structural Formula: C21H19F4N7 · C7H8O3S

MDL Number: MFCD29054739

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: LY2584702 is an orally active, ATP-competitive, potent and selective ribosomal protein S6 kinase (p70 S6 kinase, p70S6K, S6K1) inhibitor (IC50 = 4 nM; selective over 83 other kinases and 45 cell surface markers). LY2584702 inhibits HCT116 cellular S6 phosphorylation (IC50 0.1-0.24 muM) and shows anti-tumor efficacy in U87MG glioblastoma and HCT116 colon carcinoma xenograft models in vivo (2.5 mg/kg bid. po.).

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Product Detail
Thomas No.
CHM03J595
Mfr. No.
SML2892-5MG
Description
SML2892-5MG, LY2584702 tosylate >=98% (HPLC)
CAS Number
1082949-68-5
list price/quantitytotal
$0.00
Thomas No.
CHM03J596
Mfr. No.
SML2892-25MG
Description
SML2892-25MG, LY2584702 tosylate >=98% (HPLC)
CAS Number
1082949-68-5
list price/quantitytotal
$0.00
$0.00 (0 Items)
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