Antigen: synthetic peptide from human LSD1 amino acids 450-500
Host: rabbit
Cross Reactivity: (+) chimpanzee, bovine, canine, equine, human, mouse, orangutan, and porcine LSD1
Application(s): WB
LSD1 is a lysine-specific histone demethylase that acts as a component of CoREST and other transcriptional co-repressor complexes. It plays an important role in silencing neuronal-specific genes in non-neuronal cells and is also known to demethylate Lys4 of histone H3, a specific tag for epigenetic transcriptional activation.