Antigen: peptide corresponding to a portion of human LSD1 amino acids 100-150
Host: rabbit
Cross Reactivity: (+) canine, human, mouse, rat, Rhesus monkey, and zebrafish LSD1
Application(s): WB
LSD1 functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. It is typically associated with CoREST and HDACs 1 and 4 and participates in the silencing of endogenous neuron-specific genes.