Synonyms: Lenalidomide; 1-Oxo-4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole; 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione; 3-(4-Amino-1-oxoisoindolin-2-yl)piperidin-2,6-dione; 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione; CC 5013; CC-5013
Molecular Formula: C13H13N3O3
Molecular Weight: 259.26
Linear Structural Formula: C13H13N3O3
MDL Number: MFCD07772307
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Lenalidomide, a derivative of thalidomide, is an immunomodulatory agent that is approved drug for treatment of multiple myeloma. Apparently Lenalidomide is a ligand of ubiquitin E3 ligase cereblon that induces the enzyme to degrade the Ikaros transcription factors IKAROS family zinc finger 1 (IKZF1) and IKZF3. Lenalidomide possess pleiotropic antitumor effects. It is used in the treatment of 5q-deletion associated myelodysplastic syndrome (del(5q)-MDS).