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A selective ALK1 and ALK2 inhibitor (IC50s = 24 nM for each) with preference over ALK3 (IC50 = 1.17 µM) and other related activin and TGF-β type I receptors (IC50s = 3, 0.1, and 16 µM for ALK5, BMP6, and TGF-β, respectively).