Synonym: L-α-Amino-γ-(guanidinooxy)-n-butyric acid
CAS Number: 543-38-4
Empirical Formula (Hill Notation): C5H12N4O3
Molecular Weight: 176.17
MDL Number: MFCD00055781
PubChem Substance ID: 24892427
Biochem/physiol Actions
A naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Canavanine is a naturally occurring L-amino acid that interferes with L-arginine-utilizing enzymes due to its structural similarity. It is a selective inhibitor of inducible nitric oxide synthase (iNOS). Overproduction of NO by iNOS plays a crucial role in the pathophysiology of septic shock and chronic inflammation.
Biological Source: from Canavalia ensiformis
Assay: ≥98% (TLC)
Form: powder
Solubility: H2O: <100 mg/mL
Storage Temp.: 2-8°C