Synonyms: 3,5-Dibromo-4-hydroxy-benzoic acid 2-[[2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl]methylene]hydrazide; 3,5-Dibromo-N'-{[2,5-dimethyl-1-(3-nitrophenyl)-1H-pyrrol-3-yl]methylene}-4-hydroxybenzohydrazide
Molecular Formula: C20H16Br2N4O4
Molecular Weight: 536.17
Linear Structural Formula: C20H16Br2N4O4
MDL Number: MFCD02636553
Purity: >97% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Kinesore is a cell penetrant and potent activator of kinesin-1 that induces kinesin light chain tetratricopeptide repeat domain-dependent kinesin-1 activation in the absence of organelle cargo-adaptor engagement. It inhibits kinesin-1 interaction with peptide fragment of organelle-specific cargo adaptors. Kinesore induces kinesin light chain conformational switch that causes remodeling of the microtubule network in cells.