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MilliporeSigma

Jagged-2 (human): FC (human) recombinant, expressed in HEK 293 cells, >=90% (SDS-PAGE)

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Jagged-2 (human): FC (human) recombinant, expressed in HEK 293 cells, >=90% (SDS-PAGE)

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

Synonyms: Alpha-ketoglutarate-dependent dioxygenase FTO; Protein jagged-2; hJ2

Purity: >=90% (SDS-PAGE)

Storage: -20C

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Product Detail
Thomas No.
CHM03P919
Mfr. No.
SRP8059-10UG
Description
SRP8059-10UG, Jagged-2 (human): FC (human) recombinant, expressed in HEK 293 cells, >=90% (SDS-PAGE)
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