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An orally bioavailable CFTR potentiator that improves chloride transport; increases the forskolin-induced CFTR-mediated epithelial current in cells expressing the G551D mutation by ~4-fold (EC50 = 100 nM); increases chloride secretion in cultured human CF bronchial epithelial cells carrying the G551D mutation.

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Product Detail
Thomas No.
C818D34
Mfr. No.
15145-1
Description
Ivacaftor-1 mg
CAS Number
873054-44-5
Packaging Size
1 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C818D35
Mfr. No.
15145-5
Description
Ivacaftor-5 mg
CAS Number
873054-44-5
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C818D36
Mfr. No.
15145-10
Description
Ivacaftor-10 mg
CAS Number
873054-44-5
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C818D37
Mfr. No.
15145-50
Description
Ivacaftor-50 mg
CAS Number
873054-44-5
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
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