This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Synonyms: 4-Pyridinecarboxylic acid hydrazide; INH; Isonicotinic acid hydrazide; Isonicotinic hydrazide
Molecular Formula: C6H7N3O
Molecular Weight: 137.14
Linear Structural Formula: C6H7N3O
MDL Number: MFCD00006426
Melting Point: 171-173 C (lit.)
Storage: 2-8C
Biochem Physiol Actions: Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations.
Other Notes: USP issued SDS can be found here.