Synonyms: 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide; AMG-131; T0903131
Molecular Formula: C21H12Cl4N2O3S
Molecular Weight: 514.21
Linear Structural Formula: C21H12Cl4N2O3S
MDL Number: MFCD13152369
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARgamma) modulator (SPPARM) that displays anti-diabetic activities. INT131 is a partial, rather than a full agonist of PPARgamma, and in clinical trials has shown increased glucose tolerance without the weight gain and cardiovascular side effects seen with some of the full agonist.