Animal-free Recombinant Human VEGF121 is expressed in human 293 cells as a glycosylated cytokine with an apparent molecular mass of 37 kDa as dimer and 50 kDa as trimer. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media. The cytokine is produced in a human cell expression system with serum free, chemically defined media. VEGF121 is a potent growth and angioenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis amd vascular permeability.