CD19 is a 95 kDa, type I transmembrane glycoprotein that belongs to the immunoglobin superfamily. It is expressed by B cells and follicular dendritic cells and regulates B cell lineage commitment during hematopoietic stem cell differentiation. It is observed that 6%-23% human PBMC are CD19 positive. Human CD19 Magnetic Beads can be used for isolation or depletion of human CD19 B lymphocytes from PBMC, whole blood, or other sample types. Following incubation with human CD19 antibody conjugated magnetic beads, the cell sample is placed on a magnet. CD19+ cells remain attached to magnetic beads after separation and can be used for downstream applications, such as in expansion of cells, but are not suitable for flow cytometry analysis. CD19- cells remain in supernatant and could be used forfurther applications.