CD11b is the a-chain of integrin receptor CD11b/CD18 (also known as aMß2, Mac-1, and CR3), is highly expressed on the surface of innate immune cells, including macrophages, neutrophils, eosinophils and basophils. Human CD11b Magnetic Beads Kit is used for isolation or depletion of human CD11b monocytes/macrophages from PBMC, whole blood, or other sample types. Following incubation with biotinylated human CD11b antibody and Streptavidin magnetic beads, the cell sample is placed on a magnet. CD11b+ cells remain attached to magnetic beads after separation and can be used for downstream applications, such as in cell expansion. CD11b- cells remain in supernatant and can also be used for further applications.