Hydrosphere C18 is designed to maintain adequate hydrophilicity on the packing surface for superior separation of hydrophilic compounds. Hydrophilic compounds are retained with much greater affinity than with conventional ODS columns, permitting the product to be used with 100% water eluent, a problematic eluent for conventional ODS columns. Hydrosphere C18 is useful for separating a wide range of compounds, including nucleic acids and their derivatives, organic acids, saccharides, glycosides and peptides.
Application: For Nicotinic Acid and Derivatives, Nucleotides
- Based on highly inert, ultra pure, pH neutral silica
- "Hydrophilic" C18 surface for enhanced polar selectivity
- Extremely rigorous physical and chemical specification
- Suitable for conventional reversed phase and highly aqueous application
- Pharmaceutical method development