Synonyms: (1R,3S)-HPA-12; (1R,3S)-N-(3-Hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide; 16ASC1859; N-[(1R,3S)-3-Hydroxy-1-(hydroxymethyl)-3-phenylpropyl]dodecanamide; N-[(2R,4S)-1,4-Dihydroxy-4-phenylbutan-2-yl]dodecanamide
Molecular Formula: C22H37NO3
Molecular Weight: 363.53
Linear Structural Formula: C22H37NO3
MDL Number: MFCD29472535
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: (1R,3S)-HPA-12 is a ceramide (Cer) analog that acts as a Cer transporter (CERT) antagonist and selectively inhibits cellular Cer conversion to sphingomyelin (SM), but not to glucosylceramide, by blocking CERT-mediated Cer ER-to-Golgi transport. Common culture dosing range: 1-10 muM.