Antigen: synthetic peptide from human Histone H3.3 amino acids 100-136
Host: rabbit
Cross Reactivity: (+) chicken, ovine, Drosophila, equine, human, mouse, and opossum histone H3.3
Application(s): IHC and WB
Histone H3.3 constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. It has a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.