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Rockland Immunochemicals Inc

Herpesvirus 8 Monoclonal Antibody

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Herpesvirus 8 Monoclonal Antibody

Background

HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposi’s sarcoma.

Application Note

Anti-Herpesvirus 8 (RAT) Monoclonal Antibody was tested in IHC-P with positive control Karposi sarcoma tissues. Cellular Localization: Nuclear. The user is advised to validate the use of the products with their tissue specimens prepared and handled in accordance with their laboratory practices. Consult references (Kiernan, 1981: Sheehan & Hrapchak, 1980) for further details on specimen preparation.

Purity/Specificity

This antibody reacts with Herpesvirus 8. The antibody was clarified from tissue culture supernatant.

Anti-Herpesvirus 8 (RAT) Monoclonal Antibody - Mob395-01
Herpes, Herpesvirus, HHV8, latent nuclear antigen, LNA, viral gene orf 73
LANA1
IHC
Herpesvirus
Herpesvirus
Rat
Monoclonal
LN53
CCS
Recombinant Protein
Anti-Herpesvirus 8 Antibody was produced in rats by repeated immunizations with recombinant protein corresponding to the latent nuclear antigen-1 molecule of HHV8.
Liquid
0.01% (w/v) Sodium Azide
Wet Ice
Store at 2-8°C. This antibody is suitable for use until the expiration date when stored at 2-8°C. Do not use product after the expiration date printed on vial. If reagents are stored under conditions other than those specified here, they must be verified by the user. Diluted reagents should be used promptly. Unused portions of antibody preparation should be discarded after one day. The presence of precipitate or an unusual odor indicates that the antibody is deteriorating and should not be used.

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Product Detail
Thomas No.
CHM03V378
Mfr. No.
Mob395-01
Description
Herpesvirus 8 Monoclonal Antibody, 100µL, Liquid
list price/quantitytotal
$0.00
$0.00 (0 Items)

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