A highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.The product number for this product was previously 01-62-0041.To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
Synonyms: HATU
Molecular Formula: C10H15N6O · F6P
Molecular Weight: 380.23
Linear Structural Formula: C10H15N6O · F6P
MDL Number: MFCD27957364
Melting Point: 186 C (decomposes)
Legal Information: PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany