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A synthetic agonist for REV-ERBα (EC50 = 0.4 μM) that mimics the action of heme; at 10 μM inhibits the expression of the circadian target gene bmal1 and reduces glucose output by 30% in mouse primary hepatocytes by repressing the expression of several gluconeogenic genes.

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Product Detail
Thomas No.
C832L37
Mfr. No.
11931-5
Description
GSK4112-5 mg
CAS Number
1216744-19-2
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C832L38
Mfr. No.
11931-10
Description
GSK4112-10 mg
CAS Number
1216744-19-2
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C832L39
Mfr. No.
11931-25
Description
GSK4112-25 mg
CAS Number
1216744-19-2
Packaging Size
25 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C832L40
Mfr. No.
11931-50
Description
GSK4112-50 mg
CAS Number
1216744-19-2
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
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