Synonyms: 4-(4-Fluorophenyl)-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-5-pyrimidinecarboxamide; GSK 180736A
Molecular Formula: C19H16FN5O2
Molecular Weight: 365.36
Linear Structural Formula: C19H16FN5O2
MDL Number: MFCD30533616
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: GSK180736A is a potent and selective dual inhibitor of a ROCK1 (Rho-associated, coiled-coil-containing protein kinase) and GRK2 (G protein-coupled receptor kinase 2). GSK180736A binds to the GRK2 active site. GSK180736A produces a significant cardiomyocytes contraction at 1 muM.