Synonyms: 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one
Molecular Formula: C23H15F7N2O2
Molecular Weight: 484.37
Linear Structural Formula: C23H15F7N2O2
MDL Number: MFCD27937760
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: GPBAR-A is a very potent agonist of the bile acid receptor GPBA (also known as TGR5). In murine primary intestinal cultures, GPBAR-A induces an elevation in intracellular cAMP and calcium levels, and stimulates secretion of GLP-1.