Synonyms: 1-Cyclopropyl-8-(difluoromethoxy)-7-[(1R)-2,3-dihydro-1-methyl-1H-isoindol-5-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid methane sulfonic acid salt monohydrate; BMS 284756 mesylate; Ganefloxacin mesylate; Garenfloxacin mesylate; T-3811 mesylate
Molecular Formula: C23H20F2N2O4 · CH4O3S · H2O
Molecular Weight: 540.53
Linear Structural Formula: C23H20F2N2O4 · CH4O3S · H2O
MDL Number: MFCD12031996
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: Garenoxacin is a broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections. Garenoxacin has a low mutant prevention concentration and a narrow mutant selection window. Data shows that garenoxacin has anti-inflammatory properties. It significantly alleviates LPS-induced IL-8 production through the negative regulation of the ERK1/2 pathway both in the human airway epithelial cell line A549 and the monocyte cell line THP-1.