An anti-cancer natural product that acts on a variety of cellular pathways; activates caspases, inhibits anti-apoptotic proteins, alters expression of Bcl-2 and Bax; acts as a potent, slow inhibitor of Kir2.1 channels; inhibits the chymotrypsin activity of the 20S proteasome; has effects on AMPK, EGFR, and Akt/mTorc1 signaling pathways.