Synonyms: 4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile
Molecular Formula: C14H12N4OS
Molecular Weight: 284.34
Linear Structural Formula: C14H12N4OS
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.