Synonyms: Phosphomycin disodium salt; (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid; Fosfomycin; Phosphonomycin
Molecular Formula: C3H5Na2O4P
Molecular Weight: 182.02
Linear Structural Formula: C3H5Na2O4P
MDL Number: MFCD22741288
Storage: 2-8C
Application: Refer to the product's Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem Physiol Actions: Antibiotic that concentrates in kidney and bladder; reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Fosfomycin is a phosphoenolpyruvate analog that irreversibly inhibits UDP-GlcNAc enolpyruvyl tranferase (MurA), an enzyme involved in bacterial cell wall biosynthesis. As a result, the production of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall, is inhibited.
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