This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Synonyms: (+/-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid; L-790,330
Molecular Formula: C15H13FO2
Molecular Weight: 244.26
Linear Structural Formula: C6H5C6H3(F)CH(CH3)CO2H
MDL Number: MFCD00079303
Melting Point: 110-112 C (lit.)
Biochem Physiol Actions: Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.
Other Notes: Sales restrictions may apply.