Synonyms: Retinoic acid; ATRA; Tretinoin; Vitamin A acid; all-trans-Retinoic acid
Formula: C20H28O2
Formula Weight: 300.44
CAS No.: 302-79-4
Biochem/physiol Actions: all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
Grade: certified reference material
MP: 180-181°C(lit.)
Packaging: pkg of 3 × 100 mg
Pharmacopeia Traceability: traceable to USP 1674004