"N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane, for derivatization"

Silylation can be performed by adding N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MTFA) during analysis of fluorometabolites via gas chromatography-mass spectrometry (GC-MS).

Molecular Formula: C6H12F3NOSi

Molecular Weight: 199.25

Linear Structural Formula: C6H12F3NOSi

MDL Number: MFCD00000411

Purity: >=97.0%

Refractive Index: n20/D 1.378

Application: Addition of Trimethylchlorosilane aids in the derivatization of amides, secondary amines and hindered hydroxy groups. Most volatile of the TMS derivatives often elutes at the solvent front of the GC.

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