Synonyms: Methyl chloroformylacetate
CAS Number: 37517-81-0
Formula: C4H5ClO3
Formula Weight: 136.53
Linear Formula: CH3OCOCH2COCl
MDL No.: MFCD00013657
Purity: >=97.0% (AT)
Boiling Point: 57-59 C/12 mmHg(lit.)
Density: 1.273 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.432(lit.); n20/D 1.432
Storage: 2-8C
Beilstein Registry Number: 1754078
EC Number: 253-540-6
UNSPSC Code: 12352100
Application: Methyl malonyl chloride can be used in the synthesis of methyl 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-one-6-carboxylates and 6-carboxamides, which can act like HIV integrase strand transfer inhibitors. It can also be used in the synthesis of Strychnos alkaloids like (-)-leuconicine A and (-)-leuconicine B.
RIDADR: UN 3265 8 / PGII
WGK Germany: 3
Flash Point(F): 176 F
Flash Point(C): 80 C
R Codes: 34-36/37
S Codes: 26-36/37/39-45
IOD Codes: C
Symbol: GHS05, GHS07
Signal Word: Danger
Hazard Statements: H314-H335
Precautionary statements: P261-P280-P305 + P351 + P338-P310