Hexamethyldisilazane (HMDS) is a commercially available, silylating agent, which is used as an alternative for the preparation of silyl ethers from hydroxyl compounds.
Synonyms: HMDS
Molecular Formula: C6H19NSi2
Molecular Weight: 161.39
Linear Structural Formula: (CH3)3SiNHSi(CH3)3
MDL Number: MFCD00008259
Purity: >=99.0% (GC)
Refractive Index: n20/D 1.407 (lit.); n20/D 1.408
Application: Suitable for the derivatization of alcohols, Υ-aminobutyric acid, pesticidal carbamates and urea, 3,4-Dihydroxyphenylglycol, 4-hydroxycoumarins, hydroxyfatty acids, n-hydroxy-2-fluorenylacetamide, kerb cycle acid, malonaldehyde, monoglycerides, phenylpyruvic acid, shikimic acid, unsaturated fatty acid esters (or methyl esters), and related compounds.
Legal Information: LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Reagent for 2-hydroxypyrimidine, polytrimethylsilyloxy, trimethylsilyl and trimethylsilyl oximes.
Signal Word: Danger
Hazard statements: H225-H302 + H332-H311-H314-H412
Precautionary statements: P210-P273-P280-P305 + P351 + P338-P310
Hazard Codes (Europe) : F,C
Risk Statements (Europe): 11-20/21/22-34-52/53
Safety Statements (Europe): 16-26-36/37/39-45-61
WGK Germany: 2