Synonym(s): EDTA tetrasodium salt; Edathamil; Tetrasodium ethylenediaminetetraacetate hydrate
Formula: (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O
Formula Weight: 380.17 (anhydrous basis)
CAS No.: 194491-31-1
Purity: ≥97.0% (KT)
Application: EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.
Preparation Note: Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.
Beilstein Registry Number: 3861753
EC No.: 200-573-9
Empirical Formula (Hill Notation): C27H46S