Synonyms: Boc2O; Boc anhydride; Di-tert-butyl pyrocarbonate
CAS Number: 24424-99-5
Formula: C10H18O5
Formula Weight: 218.25
Linear Formula: [(CH3)3COCO]2O
MDL No.: MFCD00008805
Purity: >=98.0% (GC)
Boiling Point: 56-57 C/0.5 mmHg(lit.)
Melting Point: 22-26 C; 23 C (lit.)
Density: 0.95 g/mL at 25 C(lit.)
Refractive Index: n20/D 1.409(lit.)
Storage: 2-8C
Beilstein Registry Number: 1911173
EC Number: 246-240-1
UNSPSC Code: 12352000
Application: Reagent for the introduction of the Boc protecting group.
Application: Di-tert-butyl dicarbonate is a reagent mainly used for the introduction of the Boc protecting group.Some of its general applications include:. Clean and rapid introduction of the acid labile BOC-protecting group in amino acids, peptides and proteins. . N-BOC-ylation of amides. . N-BOC-ylation of sensitive compounds under non-aqueous conditions.It has been used in the following processes:. Synthesis of an azobenzene amino acid(aa).. Synthesis of N-tert-butoxycarbonyl-3,4-methylenedioxymethamphetamine (t-BOC-MDMA) from MDMA.
RTECS: HT0230000
RIDADR: UN 2929 3(6.1) / PGII
WGK Germany: 3
Flash Point(F): 98.6 F
Flash Point(C): 37 C
R Codes: 10-26-36/37/38-43
S Codes: 7/9-16-26-28-36/37/39-45
IOD Codes: T+
Symbol: GHS02, GHS05, GHS06
Signal Word: Danger
Hazard Statements: H226-H315-H317-H318-H330-H335
Precautionary statements: P210-P260-P280-P304 + P340 + P310-P305 + P351 + P338 + P310-P370 + P378