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MilliporeSigma

"Cyclosporin A, VETRANAL™, analytical standard"

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"Cyclosporin A, VETRANAL™, analytical standard"

Synonyms: Antibiotic S 7481F1; Cyclosporine

Formula: C62H111N11O12

Formula Weight: 1202.61

CAS No.: 59865-13-3

Biochem/physiol Actions: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.

Legal Information: VETRANAL is a trademark of Sigma-Aldrich Co. LLC

Grade: VETRANAL™, analytical standard

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Thomas No.
C990K17
Mfr. No.
32425-100MG
Description
FLUKA Cyclosporin A, VETRANAL™, analytical standard, 100 mg
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