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MilliporeSigma

"Cyclosporin A, pharmaceutical secondary standard; traceable to USP and PhEur"

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"Cyclosporin A, pharmaceutical secondary standard; traceable to USP and PhEur"

Synonyms: Antibiotic S 7481F1; Cyclosporine

Formula: C62H111N11O12

Formula Weight: 1202.61

CAS No.: 59865-13-3

Biochem/physiol Actions: A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria.

Grade: certified reference material

Packaging: pkg of 500 mg

Pharmacopeia Traceability: traceable to USP 1158504

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Product Detail
Thomas No.
C987G34
Mfr. No.
PHR1092-500MG
Description
FLUKA Cyclosporin A, pharmaceutical secondary standard; traceable to USP and PhEur, 500 mg
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