Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin.
Synonyms: HFP; Hexafluoroisopropanol
Molecular Formula: C3H2F6O
Molecular Weight: 168.04
Linear Structural Formula: (CF3)2CHOH
MDL Number: MFCD00011651
Purity: >=99.8% (GC); >=99.8%
Melting Point: -4 C (lit.)
Density: 1.596 g/mL at 25 C (lit.)
Refractive Index: n20/D 1.275 (lit.)
Application: Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid.
Legal Information: LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2-propanol
RTECS: UB6450000
RIDADR: UN 3265 8 / PGII
WGK Germany: 2
R Codes: 63-22-34-62
S Codes: 26-36/37/39-45
IOD Codes: C
Symbol: GHS05, GHS07, GHS08
Signal Word: Danger
Hazard Statements: H302-H314-H361
Precautionary statements: P260-P280-P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338