Antigen: human GPR40 amino acids 210-222
Host: rabbit
Cross Reactivity: (+) human GPR40
Application(s): IHC and WB
GPR40 is a GPCR found predominantly in the b-cells of pancreatic islets that has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse b cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes.