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MilliporeSigma

Erastin2 >=98% (HPLC)

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Synonyms: 2-((4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)methyl)-3-(4-isopropoxybiphenyl-3-yl)quinazolin-4(3H)-one; 2-[[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[4-(1-methylethoxy)[1,1'-biphenyl]-3-yl]-4(3H)-quinazolinone; 35MEW28

Molecular Formula: C36H35ClN4O4

Molecular Weight: 623.14

Linear Structural Formula: C36H35ClN4O4

Purity: >=98% (HPLC)

Storage: 2-8C

Biochem Physiol Actions: Erastin2 is an Erastin analog with greatly improved system xc- (SLC7A11/xCT + SLC3A2/4F2hc) inhibitory potency (Erastin2 IC50 = 3.5 nM/CCF-STTG1; Erastin IC50 = 200 nM/HT-1080, 140 nM/Calu-1; Glu release assay) and ferropotosis induction efficacy (HT-1080 EC50 = 150 nM/Erastin2 vs. 1.2 muM/Erastin).

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Product Detail
Thomas No.
CHM03J579
Mfr. No.
SML2794-5MG
Description
SML2794-5MG, Erastin2 >=98% (HPLC)
CAS Number
1695533-44-8
list price/quantitytotal
$0.00
Thomas No.
CHM03J580
Mfr. No.
SML2794-25MG
Description
SML2794-25MG, Erastin2 >=98% (HPLC)
CAS Number
1695533-44-8
list price/quantitytotal
$0.00
$0.00 (0 Items)
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