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A potent, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 24 nM), the enzymatic subunit of PRC2; blocks trimethylation of the PRC2 target H3K27 (IC50 = 80 nM), decreasing the proliferation of lymphoma cells carrying mutant, but not wild-type, EZH2.

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Product Detail
Thomas No.
C830J03
Mfr. No.
13966-5
Description
EPZ005687-5 mg
CAS Number
1396772-26-1
Packaging Size
5 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C830J04
Mfr. No.
13966-10
Description
EPZ005687-10 mg
CAS Number
1396772-26-1
Packaging Size
10 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C830J05
Mfr. No.
13966-25
Description
EPZ005687-25 mg
CAS Number
1396772-26-1
Packaging Size
25 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
Thomas No.
C830J06
Mfr. No.
13966-50
Description
EPZ005687-50 mg
CAS Number
1396772-26-1
Packaging Size
50 mg
Packaging Type
Bottle, Glass, Clear
list price/quantitytotal
$0.00
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