Synonyms: 3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide; 3-Cyano-N-(3-cyano-4-methyl-1H-indole-7-yl)benzensulfonamide; E 7820; NSC 719239
Molecular Formula: C17H12N4O2S
Molecular Weight: 336.37
Linear Structural Formula: C17H12N4O2S
MDL Number: MFCD09833234
Purity: >=98% (HPLC)
Storage: 2-8C
Biochem Physiol Actions: E7820 (NSC 719239) is an orally available anticancer and antiangiogenic agent that inhibits VEGF-2 or FGF-2-induced tube formation of HUVEC cells through the suppression of integrin alpha2. E7820 promotes selective proteasomal degradation of the U2AF-related splicing factor CAPERalpha (coactivator of activating protein-1 and estrogen receptors) by ubiquitination and degradation via CRL4DCAF15.