Antigen: DNMT3a expressed in bacteria
The epitope was found to be located near the C-terminus (amino acids 705-908)
Host: mouse, clone 64B1446
Isotype: IgG1κ
Cross Reactivity: (+) human and mouse DNMT3a
Application(s): ChIP, IF/ICC, IHC (paraffin), and WB
The DNMT3 family members DNMT3a and DNMT3b are strongly expressed in embryonic stem cells. Their expression is down regulated in differentiating cells and low in adult sematic tissue.