DL-Homocysteine is a thiol-containing amino acid derived from methionine.{48974} It inhibits vasodilation of precontracted isolated guinea pig pulmonary artery rings induced by acetylcholine (ACh) and enhances potassium chloride- and phenylephrine-induced contraction of isolated guinea pig pulmonary artery rings.{48975} DL-Homocysteine (200 µM) inhibits endothelium-dependent ACh-induced vasodilation in the vascular bed of isolated perfused rat pancreas.{48976} Elevated plasma levels of DL-homocysteine are positively correlated with occlusive arterial diseases and atherosclerosis.{48974,48975}
Technical Information
Formal Name
N-[(butyl-1,1,2,2,3,3,4,4,4-d9-amino)carbonyl]-4-methyl-benzenesulfonamide
CAS Number
1219794-57-6
Synonyms
D 860-d9
U-2043-d9
Molecular Formula
C12H9D9N2O3S
Formula Weight
279.4
Purity
99% deuterated forms (d1-d9)
Formulation
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A solid
Solubility
(Learn about Variance in Solubility)
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 30 mg/ml
Ethanol:PBS (pH 7.2) (1:1): 0.14 mg/ml
SMILES
CC1=CC=C(S(NC(NC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)(=O)=O)C=C1
InChi Code
InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)/i1D3,3D2,4D2,9D2
InChi Key
JLRGJRBPOGGCBT-ZYWCKPJZSA-N
Shipping & Storage Information
Storage -20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
Shelf life: 4 years